Is Galaxy Angel Rune hentai?
No
Rated PG-13 (Teens 13 or older) on MyAnimeList and not tagged as Hentai.

TV · 2006 · 13 episodes · PG-13 - Teens 13 or older
Comedy, Sci-Fi
Apricot Sakuraba and 4 new girls were now assigned as the new Galaxy Angels with the same mission: to search for the Lost Technology and keep peace to Planet Transbaal. (Source: ANN)
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