Is Happy☆Lesson Advance hentai?
No
Rated PG-13 (Teens 13 or older) on MyAnimeList and not tagged as Hentai.

TV · 2003 · 13 episodes · PG-13 - Teens 13 or older
Comedy, Harem, Romance
Hitotose Chitose is now living together with his 5 teachers as his mothers when a mysterious girl appears and becomes their neighbor which turns out that that person is Nagatsuki Kuron who wants Mu-chan to be her mother so another sibling rivalry ensues as to who would end up as Mu-chan's child. (Source: ANN)
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